Neonatal Diseases (Pathophysiology):

During the past decade, our understanding of the pathophysiology of coronary artery disease (CAD) has undergone a remarkable evolution. We review here how these advances have altered our concepts of and clinical approaches to both the chronic and acute phases of CAD. Previously considered a cholesterol storage disease, we currently view atherosclerosis as an inflammatory disorder. Aggressive management of modifiable risk factors reduces cardiovascular events and should accompany appropriate revascularization. The main evaluation factors are Cardiovascular Biology, Blood Cholesterol & Obesity, Family history, Heart Physiology and Computational Biology of Heart etc.

Childhood lungs diseases is not a disease but a group of disorders However, most lungs diseases share a common pathophysiologic feature, namely, structural remodelling of the distal airspaces, leading to impaired gas exchange. In general, this remodelling has been believed to be the sequela of persistent inflammation; however, more recently, the paradigm has shifted away from inflammation to one of tissue injury with aberrant wound healing resulting in collagenous fibrosis

 

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