Abdullah Nabi Aslan
Ankara Ataturk Education and Research Hospital, Turkey
Title: Impact of coronary artery dominance on P wave dispersion
Biography
Biography: Abdullah Nabi Aslan
Abstract
Background: P-wave duration and dispersion has been proposed as being useful for the prediction of paroxysmal atrial fibrillation (AF). The aim of this study was to investigate the effect of coronary artery dominance on P wave duration and dispersion.
Design and Methods: The study population included 194 patients with left dominant (LD) circulation and 200 age and gender-matched controls with right dominant (RD) circulation and without coronary artery dissease based on invasive coronary angiography findings. The electrocardiogram of each patients was obtained upon admission to hospital and evaluated by two cardiologists blinded to the angiographic results of the patient. P-wave dispersion (PWD) was defined as the difference between the maximum and minimum P-wave duration. Statsitical analyses were performed using SPSS v17.0 statistical software package.
Results: PWD was shown to be significantly prolonged in patients with LD circulation compared to controls with RD circulation (48 ± 14 ms vs 33 ± 15 ms, p = 0.001). P wave duration was similar between the groups (p = 0.124). Moreover, there was positive correlation between PWD and age (r: 0.502, p= 0.009), left ventricular (LV) mass (r: 0.614, p= 0.001), LV mass index (r: 0.727, p< 0.001) and left atrium (LA) diameter (r: 0.558, p= 0.003) in LD circulation patients. Multivariate logistic regression analysis determined age, LV mass index, LA diameter and LD circulation as independent predictors of prolonged PWD.
Conclusions: LD circulation could lead to an increased risk of AF through prolonged PWD. We recommend follow-up of these patients to assess the development of AF in the future.