
Robert Dumaine
Université de Sherbrooke, Canada
Biography
Robert Dumaine initiated and managed the Cardiac molecular genetic program at the Masonic Medical Research Laboratory (NY) from 1996-2004 and was Director of the Department of Physiology and Biophysics at the University of Sherbrooke from 2004-2009. He is now a Professor at the Department of Pharmacology and Physiology at the Univ. de Sherbrooke Qc. Canada. His expertise is on cardiac arrhythmias linked to potassium and sodium ion channel defects. His major contribution includes the discovery of arrhythmogenic mechanisms causing inherited and acquired forms of Long QT syndrome, Short QT syndrome and Brugada Syndrome. In collaboration with P. Schwartz laboratory, he has published the first study linking SIDS to cardiac sodium channel defects. He has pioneered research on the role of non-cardiac sodium channels in heart function and recently showed that overexpression of neuronal sodium channels in the heart could explain the QT prolongation and some of the arrhythmias observed in SUDEP and SIDS.
Abstract
Abstract : Emerging role of non-cardiac sodium channels in arrhythmias