Dr. Holmes special areas of interest include acute coronary syndromes, interventional cardiology, restenosis, vascular biology, and risk outcomes analysis. In addition, he has been involved in the development of new catheter designs for stroke prevention using left atrial appendage occlusion technology. He has been involved with the introduction and dispersion of transcatheter aortic valve replacement in the United States working with both ACC and the Society for Thoracic Surgery (STS). As part of that, he has been involved with regulatory agencies including FDA and CMS. This collaboration has led to the development of a working group on Early Feasibility Studies (EFS). Finally, he is involved in the development of continued application of percutaneous coronary intervention technology to noncoronary vascular beds.
Acute coronary syndromes, Interventional cardiology, restenosis, Vascular biology, and Risk outcomes analysis