Amira Esmat El Tantawy
Cairo University, Egypt
Title: Change in risk factors influencing cardiac functions in pediatric renal transplanted patients
Biography
Biography: Amira Esmat El Tantawy
Abstract
Cardiovascular disease accounts for the majority of deaths in children with chronic kidney disease (CKD) and post renal transplantation. The main objective of this work was to study the prevalence of the different cardiovascular risk factors presented either before or after renal transplantation measuring the LV function using conventional 2D , M mode echocardiography (left ventricular mass index (LVMI), pulsed Doppler (E/A ratio) and tissue Doppler imaging ( E’, A’, E’/A’ , and E/E’). This Cross-sectional, observational study included 30 children with renal transplantation and 10 normal children as control. Patients age of ranged from 5-14 years. Significant improvement in risk factors: Anaemia, Hypercholesterloaemia and hypertension HTN (p value 0.002, 0.005, and < 0.001 respectively) after renal transplantation was observed. Among transplanted patients, Prevalence of left ventricular hypertrophy was 93.3%. Patients have significant increase in left ventricular mass index (LVMI) than controls ( p<0.001), significant higher E/A ratio (p 0.014), and Significant lower A’ (p <0.001), Presence of HTN pre and post renal transplantation was the only risk factor significantly affecting the diastolic cardiac function with significant E/E’ (p 0.001 and p<0.001).